Table 4 Statistically significant upregulated reactome pathways after multi− omic analysis of PGVG + phytol lungs
From: Multi-omic assessment shows dysregulation of pulmonary and systemic immunity to e-cigarette exposure
Upregulated reactome | |
|---|---|
Name | P-value |
Crosslinking of collagen fibrils | 2.47E−06 |
Platelet Adhesion to exposed collagen | 2.96E−06 |
GPVI-mediated activation cascade | 0.0000237 |
Degradation of the extracellular matrix | 0.000131 |
Peptide ligand-binding receptors | 0.000439 |
Chemokine receptors bind chemokines | 0.00113 |
Class A/1 (Rhodopsin-like receptors) | 0.00182 |
GPCR ligand binding | 0.00414 |
Interleukin-1 processing | 0.00449 |
Cytokine Signaling in Immune system | 0.0245 |
GPCR downstream signaling | 0.027 |
Activation of Matrix Metalloproteinases | 0.0275 |
Signaling by GPCR | 0.039 |
Interleukin-1 signaling | 0.0398 |