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Table 1 Statistically significantly different lipids for the comparisons of Phytol vs FA and PGVG vs FA

From: Multi-omic assessment shows dysregulation of pulmonary and systemic immunity to e-cigarette exposure

 

Metabolite

FC

log2(FC)

−log10(p)

Phytol

Cer(d18:1/17:2)

0.00115

− 9.7704

1.5962

Palmitic acid

0.03538

− 4.8211

1.4527

PC 35:2

0.33585

− 1.5741

1.7379

PE 35:5

2.523

1.3352

1.0466

PE 38:4

3.6604

1.872

1.0291

PC 32:2

4.3165

2.1099

1.782

PG 32:0

4.4549

2.1554

1.1704

PE 16-0,18-1-3

5.1563

2.3663

1.209

PGVG

Cer(d18:1/22:0)

0.00015

− 12.708

5.4973

DG(18:2_18:0)

0.0002

− 12.298

4.1478

PS 38:1

0.0002

− 12.266

5.4119

Cer (d18:2/16:0)

0.0002

− 12.262

4.7184

Cer(d18:2/24:1)

0.00021

− 12.251

4.1506

LPE 18:0

0.00021

− 12.226

6.504

DG(16:0_16:0)

0.00021

− 12.194

5.694

Palmitic acid

0.00022

− 12.171

2.4323

PC(18:0/18:0)

0.00022

− 12.121

4.5752

PE 35:5

0.00023

− 12.095

3.3403

Cer(d18:1/16:0)

0.00023

− 12.095

3.3403

Cer(d18:1/25:0)

0.00023

− 12.079

4.2333

Cardiolipin (18:1)(18:1)(18:1)(18:2)

0.00024

− 12.053

2.1101

PS 34:1-1

0.00025

− 11.965

3.0063

Cer(d18:1/24:1)

0.00026

− 11.926

4.045

PE 35:3

0.00031

− 11.654

3.5414

LPE 16:0

0.00033

− 11.579

5.3328

PS 36:0-1

0.00035

− 11.475

3.5917

PG 32:0

0.00042

− 11.232

3.7891

PC 32:1

0.00052

− 10.91

2.6762

PA(12:0/12:0)

0.00057

− 10.784

2.6539

PC 36:4

0.00061

− 10.673

4.8443

PC 32:2

0.00061

− 10.673

4.8443

PC 37:7

0.00067

− 10.546

1.2964

PI 38:4–1

0.00069

− 10.498

1.6448

TG(18:1_18:1_18:1)

0.0007

− 10.477

1.6099

DG(20:4_18:1)

0.00075

− 10.386

2.4363

Stearic acid

0.00075

− 10.386

2.4363

PE(18:0/18:1)

0.00083

− 10.236

2.5514

LPC O-18:0

0.00097

− 10.015

2.3409

Cer(d18:1/24:0)

0.0011

− 9.8221

2.1698

DG(18:0_16:0)

0.00115

− 9.7704

2.504

Cer(d18:2/18:0)

0.00123

− 9.6708

2.7196

DG(20:4_16:0)

0.00125

− 9.6416

4.4494

PC 38:6

0.00132

− 9.562

4.5345

PI 36:4-1

0.00132

− 9.562

4.5345

LysoPC (15:0/0:0)

0.00143

− 9.453

2.4432

Cer(d18:2/24:0)

0.00144

− 9.4356

1.998

PE 36:4

0.00157

− 9.3148

2.9661

Cer(d18:1/17:2)

0.00179

− 9.1268

1.5558

PC 36:0

0.00195

− 9.0015

1.4976

PC 33:2

0.00211

− 8.8855

1.5757

PC 38:5

0.00231

− 8.7603

5.5134

Cer(d18:1/22:2)

0.00231

− 8.7603

5.5134

PE 34:1

0.00239

− 8.7098

3.3126

PG 34:2

0.00271

− 8.5277

3.3915

PS 36:0-2

0.00424

− 7.883

2.4486

PE 38:5

0.00888

− 6.8149

3.2615

SM (d18:1/17:0)

0.0104

− 6.5869

3.5623

PS 36:1-1

0.0148

− 6.078

2.6623

PE 38:4

0.0287

− 5.1228

3.2156

Lyso PC (18:1)

0.03076

− 5.0228

3.2135

DG(18:1_16:1)

0.09277

− 3.4303

1.5821

PC 34:0

0.24283

− 2.042

2.4338

PS 40:6-1

0.38553

− 1.3751

1.3339

PC(16:0/16:0)

2.6101

1.3841

1.4403

PE 16-0,18-1-3

2.6101

1.3841

1.4403

PC 36:1

3.1521

1.6563

1.2648

PS 36:1-2

3.371

1.7532

1.3038

PC 32:0

4.311

2.108

2.0607

PC 35:2

4.311

2.108

2.0607

DG 30:1

4.5135

2.1742

1.0087

PS 38:4-2

5.075

2.3434

1.6867

DG(18:1_18:0)

5.1499

2.3645

1.8566

PI 34:1-1

6.7075

2.7458

1.5847

PC 37:3

7.1003

2.8279

1.6506

LPC 22:0

7.3551

2.8787

1.3532

PS (12:0/12:0)

9.9955

3.3213

2.8123

PG 34:1

13.834

3.7902

2.4479

Cer(d18:1/22:1)

39.752

5.3129

3.2339

Oleic acid

561.56

9.1333

2.1111

PC 33:1

5005

12.289

4.8797

PC 40:3

7228.6

12.819

4.4114

Cardiolipin (18:1)(18:1)(18:1)(18:1)

7382.5

12.85

6.0367

LPE 18:2

7860.1

12.94

6.6564

PE (18:1/18:1)

8103.7

12.984

7.2583

PE(18:0/18:0)

9072.4

13.147

7.6326

Cer(d18:2/16:0)

9839.1

13.264

5.4926

  1. Full list of all significantly different lipids between PGVG + phytol versus FA and also PGVG versus FA from Fig. 2