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Table 1 µCT automatically extracted parameters

From: A fully automated micro‑CT deep learning approach for precision preclinical investigation of lung fibrosis progression and response to therapy

µCT readouts

 

Name

Description

Unit

Formula

From P01

\({N}_{P01}\)

Number of voxels at the end of inspiration phase (P01)

Counting of lung voxels in P01

\({V}_{P01}\)

Total lung volume at the end of inspiration phase (P01)

mm3

\({N}_{P01}\cdot \mathrm{voxel size}\)  

\({MLA}_{P01}\)

Mean lung attenuation at the end of inspiration phase (P01)

HU

\(\sum_{i=1}^{ {N}_{P01}}{\left(HU\right)}_{i}/{N}_{P01}\)

Air

Volume of air at the end of inspiration phase (P01)

mm3

\(\frac{{\mathrm{V}}_{\mathrm{P}01}\cdot {\mathrm{MLA}}_{\mathrm{P}01}}{-1000(\mathrm{HU})}\)  

From P02

\({N}_{P02}\)

Number of voxels at the end of expiration phase (P02)

Counting of lung voxels in P02

\({V}_{P02}\)

Total lung volume at the end of expiration phase (P02)

mm3

\({N}_{P02}\cdot \mathrm{voxel size}\)  

\({MLA}_{P02}\)

Mean lung attenuation at the end of expiration phase (P02)

HU

\(\sum_{i=1}^{ {N}_{P02}}{\left(HU\right)}_{i}/{N}_{P02}\)

FRC

Functional residual capacity: Volume of air at the end of inspiration phase (P02)

mm3

\(\frac{{\mathrm{V}}_{\mathrm{P}02}\cdot {\mathrm{MLA}}_{\mathrm{P}02}}{-1000(\mathrm{HU})}\)