Table 1 Demographics and clinical features of the study cohort
HIV + COPD + | HIV + COPD − | HIV − COPD + | HIV − COPD − | P* | |
|---|---|---|---|---|---|
n | 18 | 16 | 22 | 20 | – |
Age (years) | 56 (52–63) | 56 (53–61) | 69 (64–73) | 64 (56–68) | 1.02 × 10–03 |
Females (%) | 22 | 13 | 45 | 60 | 0.01 |
BMI (kg/m2) | 24.06 (19.16–26.68) | 26.81 (23.09–27.52) | 24 (22.86–29.50) | 25.25 (21.4–29.39) | 0.17 |
Smoking status | – | – | – | – | 1.58 × 10–04 |
Current (%) | 61 | 19 | 40 | 5 | – |
Former (%) | 28 | 50 | 55 | 35 | – |
Never (%) | 5.5 | 25 | 5 | 60 | – |
Unreported (%) | 5.5 | 6 | 0 | 0 | |
Pack-year history | 38 (30–49) | 4.50 (0.75–23.25) | 40 (20–50) | 20 (0–30) | 2.02 × 10–04 |
Bronchiectasis (%) | 11 | 25 | 0 | 5 | – |
Asthma (%) | 0 | 25 | 5 | 0 | – |
Pre FEV1% | 80.80 (55.55–90.10) | 83.00 (78.70–91.50) | 70.00 (59.88–78.53) | 88.75 (81.50–96.25) | 3.47 × 10–03 |
Pre FEV1/FVC | 64.61 (59.06–75.36) | 75.00 (71.64–80.59) | 63.45 (59.93–69.50) | 75.90 (72.85–81.25) | 3.46 × 10–06 |
Undetectable HIV viral load (%) | 89 | 63 | – | – | 0.16 |
CD4 T cell count (cells/mm3) | 450.0 (260.0–510.0) | 460.0 (110.0–620.0) | – | – | 0.91 |
On ART (%) | 94 | 81 | – | – | 0.32 |