Table 1 Baseline patient characteristics
|  | Total (n = 59) | Mild ARDS (n = 11) | Moderate ARDS (n = 29) | Severe ARDS (n = 19) | p value |
|---|---|---|---|---|---|
Age, yr | 59.2 (15.6) | 55.3 (13.5) | 58.6 (16.5) | 62.0 (15.7) | 0.53 |
Sex, male, % | 40 (67.8%) | 6 (54.5%) | 18 (62.1%) | 15 (78.9%) | 0.28 |
BMI | 24.6 (3.2) | 23.7 (3.0) | 24.0 (2.9) | 26.1 (3.3) | 0.06 |
Leukocytes, % | 12.7 (6.7) | 12.3 (4.1) | 12.1 (6.5) | 13.9 (8.3) | 0.68 |
Neutrophils, % | 85.3 (7.6) | 85.4 (3.1) | 84.4 (9.8) | 87.0 (5.1) | 0.55 |
CRP, mg/L | 137.0 (104.9) | 148.2 (118.0) | 115.0 (90.0) | 163.2 (115.8) | 0.30 |
IL-6, ng/L | 433.0 (915.9) | 157.6 (178.8) | 275.6 (540.9) | 837.3 (1409.3) | 0.07 |
PCT, ng/mL | 16.5 (27.9) | 4.2 (7.6) | 16.9 (31.1) | 23.4 (29.2) | 0.20 |
PaO2/FiO2 ratio | 155.4 (83.9) | 284.2 (60.5) | 148.3 (29.0) | 73.3 (18.8) | <0.01* |
Admission diagnosis, n (%) | |||||
 Trauma | 13 (22.0%) | 2 (18.2%) | 8 (27.6%) | 3 (15.8%) | 0.56 |
 Sepsis | 12 (20.3%) | 1 (9.1%) | 7 (63.6%) | 4 (21.1%) | 0.51 |
 Pneumonia | 10 (16.9%) | 3 (27.3%) | 5 (17.2%) | 2 (10.5%) | 0.57 |
 Respiratory failure | 5 (8.5%) | 1 (9.1%) | 1 (3.4%) | 3 (15.8%) | 0.32 |
 Intracranial hemorrhage | 8 (13.6%) | 4 (36.4%) | 3 (10.3%) | 1 (5.3%) | 0.07 |
 Severe pancreatitis | 11 (18.6%) | 0 (0.0%) | 5 (17.2%) | 6 (31.5%) | 0.16 |
ARDS risk factor, n (%) | 0.44 | ||||
 Directa | 25 (42.3%) | 6 (54.5%) | 13 (44.8%) | 6 (31.6%) |  |
 Indirectb | 34 (57.6%) | 5 (45.5%) | 16 (55.2%) | 13 (68.4%) |  |
APACHE II | 20.0 (7.5) | 15.0 (5.7) | 19.6 (6.7) | 23.5 (8.1) | 0.02* |
SOFA | 11.5 (4.1) | 8.9 (2.3) | 11.3 (4,2) | 13.4 (3.9) | 0.03* |
ICU duration, days | 28.2 (19.6) | 32.5 (15.0) | 30.7 (23.7) | 21.7 (12.6) | 0.23 |
Death in ICU, % | 24 (40.7%) | 1 (9.1%) | 12 (41.4%) | 11 (57.9%) | 0.02* |