Fig. 2

Identification of characteristic FRGs and immune infiltration analysis. A1 Lasso regression and A2 SVM analysis. B Venn plot for the overlapping genes between the results of Lasso regression and SVM analysis. C Heatmap of the three characteristic genes in GSE2411 and GSE109913. D The correlation among the three characteristic genes. E1 Immune landscape in ALI (GSM45427–GSM45432) and control (GSM45439–GSM45444) samples based on CIBERSORT analysis in GSE2411 datasets. E2 The distribution patterns of 22 immune cells between the ALI and control group in GSE2411 datasets. F The correlation of three core genes with immune cell infiltration (p < 0.05). G Heatmap of correlation analysis of Cp and its related up-regulated genes. H Heat map of correlation analysis of Slc7a11 and its related up-regulated genes. I Heatmap of correlation analysis of Slc39a14 and its related up-regulated genes. J The GSEA of top 20 related functions based on the correlation analysis of Cp. K The GSEA of top 20 related functions based on the correlation analysis of Slc7a11. L The GSEA of top 20 related functions based on the correlation analysis of Slc39a14. ns, not significant; *p < 0.05. **p < 0.01