Fig. 1

Identification of candidate FRGs. A1 Volcano map of DEGs between acute lung injury group and control group in GSE2411 dataset. A2 Heatmap of DEGs from GSE2411 dataset. B1 Volcano map of DEGs between acute lung injury group and control group in GSE109913 dataset. B2 Heatmap of DEGs from GSE109913 dataset. C Venn plot of upregulated overlapping genes in two datasets. D Venn plot of downregulated overlapping genes in two datasets. E1 GO enrichment analysis of DEGs. E2 KEGG pathway enrichment analysis of DEGs. F1 Volcano map of FRGs between acute lung injury group and control group in GSE2411 dataset. F2 Heatmap of FRGs from GSE2411 dataset. G1 Volcano map of FRGs between acute lung injury group and control group in GSE109913 dataset. G2 Heatmap of FRGs from GSE109913 dataset. H Venn plot for the overlapping genes between FRGs and DEGs. I The expression level of the nine candidate FRGs in the ALI group and control group of GSE2411 dataset. J The expression level of the nine candidate FRGs in the ALI group and control group of GSE109913 dataset. K1 GO enrichment analysis of the nine candidate FRGs. K2 KEGG pathway enrichment analysis of the nine candidate FRGs. L Correlation of top 5 KEGG results with the nine candidate FRGs. ns, not significant; *p < 0.05; **p < 0.01