sECMO group (n = 72) | dsECMO group (n = 81) | P | |
---|---|---|---|
Age, y | 60.5 (49.0–69.0) | 65.0 (53.5–71.5) | 0.06 |
Sex, male, n (%) | 56 (77.8) | 64 (79.0) | > 0.99 |
BMI, kg/m2, a | 23.6 (21.8–29.0) | 24.8 (22.4–28.3) | 0.38 |
Past medical history | |||
Hypertension, n (%) | 23 (31.9) | 32 (39.5) | 0.40 |
Diabetes, n (%) | 21 (29.2) | 18 (22.2) | 0.36 |
Chronic kidney disease, n (%) | 8 (11.1) | 6 (7.4) | 0.58 |
COPD, n (%) | 6 (8.3) | 7 (8.6) | > 0.99 |
Asthma, n (%) | 3 (4.2) | 4 (4.9) | > 0.99 |
Interstitial lung diseases, n (%) | 5 (6.9) | 6 (7.4) | > 0.99 |
Lung cancer, n (%) | 3 (4.2) | 7 (8.6) | 0.34 |
Chronic heart failure, n (%) | 3 (4.2) | 6 (7.4) | 0.50 |
Interval MV-ECMO > 7 days, n (%) | 4 (5.6) | 13 (16.1) | 0.04 |
Primary reason for ARDS, n (%) | 0.11 | ||
Pneumonia | 58 (80.6) | 68 (84.0) | |
Bacterial | 28 (38.9) | 19 (23.5) | |
Influenza | 9 (12.5) | 6 (7.4) | |
COVID-19 | 11 (15.3) | 20 (24.7) | |
Others | 10 (13.9) | 23 (28.4) | |
Extra-pulmonary | 5 (6.9) | 6 (7.4) | |
Drowning | 5 (6.9) | 5 (6.2) | |
Trauma | 4 (5.6) | 2 (2.5) | |
Use of muscle relaxants before ECMO support, n (%) | 27 (37.5) | 36 (44.4) | 0.41 |
Prone positioning before ECMO support, n (%) | 5 (6.9) | 10 (12.4) | 0.29 |
SOFA score at ECMO instauration | 12.5 (11.0–14.0) | 13.0 (12.0–15.0) | 0.10 |
PF ratio just before ECMO instauration | 70.9 (57.8–90.0) | 74.0 (55.4–95.6) | 0.59 |
PEEP at the timing of CT examination, cmH2O | 10 (8–12) | 10 (10–14) | 0.13 |
Use of steroid within the first 2 weeks of ECMO support, n (%) | 35 (48.6) | 48 (60.0) | 0.19 |
Use of muscle relaxants within the first 48 h of ECMO support, n (%) | 32 (44.4) | 44 (54.3) | 0.26 |
Prone positioning within the first 2 weeks of ECMO support, n (%) | 3 (4.2) | 4 (4.9) | > 0.99 |
Duration of ECMO run, days | 7.0 (5.3-9.0) | 19.0 (15.0-28.5) | < 0.001 |
Re-canulation of ECMO, n (%) | 0 (0.0) | 11 (13.6) | < 0.001 |
Mortality at 14 days after ECMO support, n (%) | 0 (0.0) | 8 (9.9) | 0.007 |
Mortality at hospital discharge, n (%) | 9 (12.5) | 49 (60.5) | < 0.001 |