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Fig. 1 | Respiratory Research

Fig. 1

From: Dysbiosis of the intestinal fungal microbiota increases lung resident group 2 innate lymphoid cells and is associated with enhanced asthma severity in mice and humans

Fig. 1

Mice were provided with cefoperazone-medicated water as the only source of water for an entire week. This was followed by a single gavage of live C. albicans or water (control), and intranasal challenge with house dust mite (HDM). The gavage of C. albicans to antibiotic depleted mice resulted in an intestinal dysbiosis state characterized by an enhanced intestinal Candida population that persisted weeks after discontinuation of the antibiotic. Mice with Candida gut dysbiosis were phenotypically normal and Candida was not detected in the lungs of mice with dysbiosis above control baseline by PCR.

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Respiratory Research

ISSN: 1465-993X

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