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Table 1 Clinical and demographic characteristics of the patients

From: IRAK-M has effects in regulation of lung epithelial inflammation

rs1624395/rs1370128

AA/TT

AG/TC

GG/CC

N

35

78

24

Mean age (y)

46.7 ± 16.4

45.1 ± 14.7

41.7 ± 14.7

Male, n (%)

16 (45.7)

24 (30.8)

11 (45.8)

Blood LnEos

5.1 ± 2.1

4.3 ± 2.4

5.5 ± 0.7

Serum LnIgE

4.2 ± 1.9

4.1 ± 2.3

5.5 ± 1.8

Pulmonary function measures

   

 FEV1 (L)

2.1 ± 1.1

2.1 ± 1.1

2.4 ± 1.0

 FVC (L)

3.1 ± 1.5

2.8 ± 1.5

3.3 ± 1.3

 FEV1% pred (%)

65.6 ± 27.3

70.2 ± 36.8

71.7 ± 24.5

 FEV1/FVC (%)

59.5 ± 22.8

61.4 ± 29.0

66.3 ± 17.9

ICS, n (%)

20 (57.1)

50 (64.1)

13 (54.2)

CXCL10 (ng/ml)

38.1 ± 3.3

41.6 ± 15.6

41.4 ± 7.8

  1. Eos: eosinophil; LnEos: loge of blood eosinophil; LnLgE: loge of total serum IgE; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; ICS: inhaled corticosteroids