Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

Respiratory Research

Table 3 Unadjusted and Adjusted (for age, sex, and BMI) Spearman’s Rank Correlations between a Subset of Circulating Biomarkers and Their Lung Gene Expression Levels Captured Through Microarray Analysis

Protein	Gene Symbol	Unadjusted r-value	Unadjusted p-value	Adjusted r-value	Adjusted p-value
Activin A	INHBA	-0.14	0.052	-0.13	0.074
ADAMTS13	ADAMTS13	0.05	0.489	0.05	0.536
Eotaxin	CCL11	0.28	< 0.001	0.18	0.017
GDF15	GDF15	0.24	0.001	0.21	0.005
MCP1	CCL2	0.11	0.144	0.10	0.172
MDC	CCL22	0.29	< 0.001	0.28	< 0.001
MMP7	MMP7	0.44	< 0.001	0.42	< 0.001
PARC	CCL18	0.34	< 0.001	0.30	< 0.001
RAGE	AGER	0.38	< 0.001	0.39	< 0.001
TARC	CCL17	0.32	< 0.001	0.26	< 0.001

ISSN: 1465-993X