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Table 1 Demographic and Clinical Characteristics of IPF and Control Participants

From: Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

 

Control

(n = 85)

IPF

(n = 95)

p-value

Age, years

mean ± SD

63.40 ± 10.48

64.81 ± 8.72

0.411*

Sex, females

n (%)

45 (52.9%)

33 (34.7%)

0.014 †

BMI, Kg/m 2

Mean ± SD

29.51 ± 6.40

30.38 ± 5.90

0.202*

Ever Smoked (> 100)

n (%)

5 (6.5%)

11 (11.8%)

0.236†

Pack Years

Mean ± SD

36.75 ± 35.31

27.26 ± 21.98

0.289*

FVC, % predicted

Mean ± SD

94.51 ± 12.97

68.42 ± 14.59

< 0.001 *

DLCO, % predicted

Mean ± SD

83.66 ± 16.62

52.67 ± 16.56

< 0.001 *

FEV1, % predicted

Mean ± SD

95.20 ± 12.66

75.59 ± 16.05

< 0.001 *

SGRQ

Mean ± SD

12.48 ± 15.52

40.03 ± 19.67

< 0.001 *

SF-12

Mean ± SD

48.09 ± 11.28

38.15 ± 10.47

< 0.001 *

6MWT, meters

Mean ± SD

418.18 ± 118.42

387.16 ± 89.15

0.004 *

  1. Abbreviations: BMI = Body Mass Index; FEV1 = Forced Expiratory Volume in 1 s; FVC = Forced Vital Capacity; DLCO = Diffusing Capacity of the Lung for Carbon Monoxide; LTRC = Lung Tissue Research Consortium; 6MWT = Six Minute Walk Test; SF-12 = 12-item Short Form Health Survey; SGRQ = St. George Respiratory Questionnaire.
  2. * p-value represents the comparison between IPF and control participants using the Kruskal-Wallis rank sum test.
  3. † p-value represents the comparison between IPF and control participants using the Pearson’s chi-squared test.
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Respiratory Research

ISSN: 1465-993X

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