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Fig. 6 | Respiratory Research

Fig. 6

From: Classical monocyte-derived macrophages as therapeutic targets of umbilical cord mesenchymal stem cells: comparison of intratracheal and intravenous administration in a mouse model of pulmonary fibrosis

Fig. 6

Effect of MSCs on mRNA expression of lung in a murine fibrosis model. A–C Changes in Il17a, Rorc, Ifng, Tbx21, Il5, Il13, Gata3, and Il10 mRNA expression by MSCs in the lungs. D Changes in Itgax, Igtam, Mrc1, and Cd86 mRNA expression by MSCs in the lungs. All data were analyzed via real-time quantitative PCR analysis. n = 5 for each group, *indicates P < 0.05, **indicates P < 0.01, ***indicates P < 0.001, ****indicates P < 0.0001. All results are representative of at least three independent experiments. MSC mesenchymal stem cell, IL interleukin, IFN interferon

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