Fig. 1From: Classical monocyte-derived macrophages as therapeutic targets of umbilical cord mesenchymal stem cells: comparison of intratracheal and intravenous administration in a mouse model of pulmonary fibrosisPathophysiologic changes in samples of patients with IPF. A H&E stain and MT stain (× 40 and × 100) of lung tissue of patients with IPF. B Changes in FN1, COL1A1, and TGB1 mRNA expression in lungs of patients with IPF. C Changes in IL17A, RORC, IL5and IL13 mRNA expression in lungs of patients with IPF. D Changes in ITGAX and ITGAM mRNA expression in lungs of patients with IPF. E MRC1, HLA-DRA CD163, and CD86 mRNA expression in lungs of patients with IPF. F CCL2 and CCR2 mRNA expression in lungs of patients with IPF. n = 5 for each group, *indicates P < 0.05, **indicates P < 0.01. All results are representative of at least three independent experiments. IPF idiopathic pulmonary fibrosis, H&E hematoxylin and eosin, MT Masson's trichrome, IL interleukinBack to article page