Table 2 Main clinical outcomes

PaO₂/FiO₂ ratio

 Baseline

123.6 ± 54.0

(111.0–136.2)

123.2 ± 51.0

(11.3–135.0)

 Day 5

208.6 ± 92.1

(186.9–230.4)

227.9 ± 97.5

(204.7–251.1)

 Difference Day 5—Baseline^a

85.0 ± 84.3

(65.0–105.0)

104.7 ± 90.5

83.1–126.3)

 Death at 90 days

22 (31%, 20–42%)

23 (32%, 21–44%)

 SOFA at day 7^c

9.0 ± 4.7 (7.7–10.3)

8.6 ± 4.7 (7.3–9.9)

 SOFA at day 14^d

9.7 ± 5.7 (7.7–11.8)

10.5 ± 5.1 (8.7–12.3)

 SOFA at day 28^e

10.8 ± 5.7 (7.1–14.4)

8.8 ± 5.6 (5.6–12.0)

Duration of ventilation

 Including pauses in d

11 (11–14, 8–14)

11 (7–14, 9–14)

 ICU length of stay in d

16 (10–34, 14–23)

17 (12–43, 14–28)

 Ventilator associated pneumonia^f

5 (7%, 2–15%)

5 (7%, 2–16%)

 ICU acquired weakness^g

7 (10%, 4–19%)

4 (6%, 2–14%)

Discharge location^h

 Home

20 (41%, 27–58%)

19 (40%, 26–55%)

 Skilled nursing facility

1 (2%, 0–11%)

1 (2%, > 0–11%)

 Rehabilitation unit

3 (6%, 1–17%)

6 (13%, 5–25%)

 Other transfer unit

25 (51%, 36–66%)

22 (46%, 31–61%)