Fig. 3From: Effects of gastroesophageal reflux disease treatment with proton pump inhibitors on the risk of acute exacerbation and pneumonia in patients with COPDIncidence rate ratios of study outcomes in patients with incident chronic obstructive pulmonary disease. In population 1, the IRRs of moderate and severe exacerbation and pneumonia during the PPI treatment period were calculated compared to that at the baseline. Population 2 comprised patients with an observation period of at least 90 days of after PPI discontinuation, and the IRRs of moderate and severe exacerbation and pneumonia during the PPI treatment and post-treatment periods were calculated. AE acute exacerbation, IRR incidence rate ratio, CI confidence interval, PPI proton pump inhibitorBack to article page