Table 4 Degree of dyspnea, state of health, exercise capacity, analytical determinations and radiological involvement at 12 months depending on the presence or absence of DLNO < LLN
Variables | DLNO ≥ LLN | DLNO < LLN | P |
|---|---|---|---|
Dyspnea according to mMRC | N = 151 | N = 36 | |
Dyspnea ≥ 1, N (%) | 58 (38.4) | 14 (41.7) | 0.60 |
Dyspnea ≥ 2, N (%) | 14 (9.3) | 7 (20.4) | 0.04 |
Dyspnea | 0 (0–1) | 0 (0–1) | 0.42 |
Health status according to Nottingham Health Profile | N = 150 | N = 33 | |
Energy | 0 (0–33.3) | 0 (0–33.3) | 0.15 |
Pain | 12.5 (0–37.5) | 12.5 (0–25) | 0.33 |
Physical mobility | 12 (0–37.5) | 25 (0–37.5) | 0.72 |
Emotional reactions | 11.1 (0–33.3) | 11.1 (0–33.3) | 0.70 |
Sleep | 20 (0–60) | 20 (0–60) | 0.52 |
Social isolation | 0 (0–0) | 0 (0–1) | 0.46 |
Number of limited areas | 3 (1–5) | 3 (1–5) | 0.95 |
Exercise capacity (6MWT) | N = 142 | N = 34 | |
Distance, m | 519.5 (472.5–562.2) | 487.5 (359.7–547.7) | 0.02 |
Initial oxygen saturation, % | 98 (97–98) | 97 (96–98) | 0.004 |
Final oxygen saturation, % | 97 (96–98) | 96 (94–97) | 0.001 |
Initial Borg scale dyspnea (1–10) | 0 (0–1) | 0 (0–1) | 0.16 |
Final Borg scale dyspnea (1–10) | 2 (0–5) | 2 (0–4) | 0.40 |
Laboratory parameters | N = 151 | N = 35 | |
D-dimer, ng/mL | 312 (215–458) | 395 (253–738) | 0.01 |
Lactate deshydrogenase, U/L | 192 (173–211) | 184 (173–203) | 0.10 |
Chest X-ray | N = 151 | N = 37 | |
Persistence of any lung injuries, N (%) | 9 (6) | 2 (5.6) | 0.9 |
Chest CT | N = 44 | N = 22 | |
Score extension affectation | 5.5 (2–8.7) | 4 (3–8.2) | 0.84 |
Ground glass opacities > 25%, N (%) | 8 (18.2) | 4 (18.2) | 0.90 |
Presence of reticulation, N (%) | 10 (22.7) | 10 (45.4) | 0.05 |
Presence of bronchiectasis, N (%) | 13 (29.5) | 7 (31.8) | 0.95 |