Fig. 5
From: SLC38A6 expression in macrophages exacerbates pulmonary inflammation
Slc38a6 promotes inflammation by affecting macrophage function. Il-1β (A), Tnf-α (B), Inos (C) relative expression level detected by RT-qPCR between SLC38A6+/− and SLC38A6−/− stimulated BMDM (n = 3). Tlr4 (D), Slc38a6 (E) and Il-1β (F) expression level between Tlr4+/− and Tlr4−/− stimulated peritoneal macrophages. G Slc38a6 expression level by LPS stimulation with or without TAK242 in RAW264.7. Slc38a6 (H) and Il-1β (I) relative expression level between PLJM-SLC38A6 and PLJM cells. Data are presented as mean ± SEM of three independent experiments. *p < 0.05