Fig. 1
From: Blocking RAGE expression after injury reduces inflammation in mouse model of acute lung injury
H&E staining. The whole lung section from mouse receiving PBS nasal instillation shows normal lung architecture. The lung from mouse receiving LPS nasal instillation in contrast shows intense and consolidated centro-lobular infiltration of inflammatory cells. The lung from the LPS injured mouse treated with non-immune IgG also shows dense staining indicating extensive infiltrates. The section from the LPS injured mouse treated with anti-RAGE ab shows visually less inflammatory infiltrates