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Table 1 Characteristics of subjects included in the study

From: Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls

 

LMSCs

AD-MSCs

BM-MSCs

Control (n = 7)

COPD (n = 7)

Control (n = 3)

COPD (n = 4)

Control (n = 7)

COPD (n = 7)

Gender

4 F / 3 M

5 F / 2 M

1 F / 2 M

3 F / 1 M

1 F / 6 M

2 F / 5 M

Smoking history

 Current

14%

14%

33%

0%

Unknown

Unknown

 Former

28%

86%

33%

100%

Unknown

Unknown

 Never

43%

0%

33%

0%

Unknown

Unknown

Age [years]

67 (41–74)

61 (45–74)

66 (41–69)

61 (45–66)

51 (43–57)

51 (44–55)

FEV1%Pred

92 (71–110)

19 (13–49)

109 (92–115)

18,5 (13–24)

Unknown

Unknown

FEV1/FVC

78 (66–81)

27 (22–24)

79 (69–80)

23,5 (22–27)

Unknown

Unknown

  1. FEV1%Pred = Predicted value for Forced Expiratory Volume in 1 s; FEV1 = Forced Expiratory Volume in 1 s; FVC = Forced Vital Capacity. For age, FEV1%Pred and FEV1/FVC, group medians with ranges are shown. For bone marrow donors, the diagnosis of COPD was confirmed by CT scan and histology. Exclusion criteria for subject inclusion in the study were the diagnosis of asthma, indications of lung infection, COPD GOLD stage classification of I or II, alpha-1 antitrypsin deficiency or abnormalities in tissue structure