Fig. 10

The miRNA biomarker candidates for asthma. Biomarker analysis was performed using prior knowledge from IPA. There are four miRNA biomarkers categories (efficacy, safety, diagnosis, and disease progression), and each category is connected to the molecules in the network by solid black lines. Nodes represent the molecules and lines indicate the relationship between two nodes. Green nodes represent downregulated miRNAs, and the upregulated ones are in pink or red. All mRNA targets, except MMP9, are represented in V-shaped dark pink. Each group of miRNAs is pointing to its specific mRNA target. BM: Biomarker