Table 3 Mortality analyses and changes in pulmonary function during follow-up
From: Clusters of comorbidities in fibrotic hypersensitivity pneumonitis
Parameter | Cluster 1 (n = 99) | Cluster 2 (n = 65) | Cluster 3 (n = 47) |
|---|---|---|---|
Cause of death, n (%) | |||
Respiratory | 4 (66.7%) | 4 (23.5%) | 1 (33.3%) |
Cardiovascular | 0 (0.0%) | 7 (41.2%) | 0 (0.0%) |
Unknown | 2 (33.3%) | 6 (35.3%) | 2 (66.7%) |
Mortality, univariate (95% CI) | 1.26 (0.31 to 5.09) | 5.58 (1.62 to 19.28) | Ref |
Mortality, multivariate (95% CI) | 2.19 (0.39 to 12.37) | 5.83 (1.21 to 28.06) | Ref |
ΔFVC, % predicted (95% CI) | − 1.9 (− 3.2 to − 0.6) | − 1.8 (− 3.0 to − 0.6) | − 1.6 (− 2.8 to − 0.3) |
ΔDLCO, % predicted (95% CI) | − 0.7 (− 2.2 to 0.7) | − 1.8 (− 3.2 to − 0.4) | − 0.7 (− 2.3 to 0.9) |
Δ6MWD, m (95% CI) | − 8.5 (− 22.7 to 5.7) | − 12.0 (− 20.1 to − 3.8) | − 10.9 (− 19.4 to − 2.4) |