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Fig. 2 | Respiratory Research

Fig. 2

From: Higher circulating Trimethylamine N-oxide levels are associated with worse severity and prognosis in pulmonary hypertension: a cohort study

Fig. 2

Kaplan–Meier analysis for the incidence of composite outcome events. PH patients (n = 163, P < 0.001 (A), IPAH/HPAH patients (n = 36, P = 0.010 (B), CHD-PAH (n = 76, P < 0.001, (C), and CTEPH (n = 51, P = 0.170 (D) were analysed. Composite outcome events include death, rehospitalisation due to heart failure, and at least 15% decreased 6MWD from the baseline. P-value calculated by the log-rank test. TMAO trimethylamine-N-oxide; PH pulmonary hypertension; IPAH/HPAH idiopathic/heritable pulmonary arterial hypertension; CHD-PAH pulmonary arterial hypertension associated with congenital heart disease; CTEPH chronic thromboembolic pulmonary hypertension; 6MWD 6-min walk distance

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