Fig. 2
From: Gut microbiota modulates bleomycin-induced acute lung injury response in mice
Conventionalizing germ-free littermates in two SPF facilities modulate the severity of lung injury response. A Germ-free C57BL/6 male littermates were transferred into either of the two SPF facilities and conventionalized for 14 days by adding dirty bedding and feces from neighboring cages twice a week. Conventionalized ex-GF mice were treated with 1.0 U/kg intratracheal bleomycin and monitored daily for survival and weight loss. B Survival and C weight loss of conventionalized ex-GF mice after bleomycin challenge. P-values were obtained from log-rank test and 2-way ANOVA, respectively, and depicted as P < 0.05 (*), P < 0.01 (**), P < 0.001 (***)