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Fig. 3 | Respiratory Research

Fig. 3

From: Activation of cannabinoid-2 receptor protects against Pseudomonas aeruginosa induced acute lung injury and inflammation

Fig. 3

Genetic deletion of CB2R worsens PA-induced lung injury and inflammation. CB2KO and WT mice were pre-treated with JWH133 and exposed PA. Control mice received i.t. injections of PBS. BALF was collected after 24 h and total cell number (a), and total protein content (b) were determined. ELISA detection of inflammatory cytokines IL-1β (c), TNF-α (d), and chemokines KC (e) and MIP-2 (f) in the BALF at 24 h after PA exposure. n = 5-8, **p < 0.01, ***p < 0.001, ****p < 0.0001. Data are presented as mean ± SEM

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