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Fig. 5 | Respiratory Research

Fig. 5

From: CircGSAP alleviates pulmonary microvascular endothelial cells dysfunction in pulmonary hypertension via regulating miR-27a-3p/BMPR2 axis

Fig. 5

Effects of miR-27a-3p on the proliferation, migration and mortality of PMECs. A Expression levels of miR-27a-3p in PMECs treated with miR-27a-3p inhibitor (n = 3). B–E Cell proliferation analysis, wound healing analysis, cell migration analysis and cell mortality analysis of PMECs with miR-27a-3p inhibitor under hypoxia (n = 5 or 4). F–I Cell proliferation analysis, wound healing analysis, cell migration analysis and cell mortality analysis of PMECs cotransfected with circGSAP and miR-27a-3p inhibitor under normoxia (n = 5 or 4). All data are presented as the mean ± SEM. Scale bar 100 μm. *p < 0.05; **p < 0.01; ***p < 0.001

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