Lung function and QoL-questionnaires | TIS | Â | Â | Placebo | Â | Â |
---|---|---|---|---|---|---|
 | Start | End | p-value | Start | End | p-value |
Pulmonary function | Â | Â | Â | Â | Â | Â |
 FEV1% predicted, mean (SD) | 65.9 (24.9) | 72.7 (23.0) | 0.58 | 70.5 (24.0) | 73.2 (23.5) | 0.21 |
 FVC% predicted, mean (SD) | 84.4 (20.1) | 85.0 (24.3) | 0.32 | 90.2 (18.6) | 90.3 (19.5) | 0.52 |
QoL-Bronchiectasis questionnaire, mean (SD) | Â | Â | Â | Â | Â | Â |
 QoL-B Physical | 49.8 (30.0) | 47.6 (27.4) | 0.75 | 42.5 (34.8) | 42.7 (38.4) | 0.47 |
 QoL-B Role | 64.4 (24.7) | 65.1 (20.7) | 0.81 | 59.2 (23.9) | 57.9 (23.9) | 0.77 |
 QoL-B Vitality | 53.1 (17.4) | 51.5 (18.7) | 0.85 | 48.7 (17.6) | 45.5 (24.5) | 0.25 |
 QoL-B Emotional | 87.9 (10.5) | 83.3 (11.2) | 0.05 | 82.4 (16.5) | 84.1 (12.8) | 0.57 |
 QoL-B Social | 65.0 (20.9) | 64.8 (16.8) | 0.81 | 60.1 (23.4) | 67.2 (18.6) | 0.10 |
 QoL-B Treatment Burden | 66.4 (17.9) | 63.9 (24.2) | 0.66 | 64.0 (19.4) | 62.8 (21.7) | 0.75 |
 QoL-B Health perceptions | 42.4 (16.8) | 48.1 (19.7) | 0.08 | 43.2 (18.9) | 46.1 (17.5) | 0.24 |
 QoL-B respiratory symptoms | 56.1 (17.8) | 61.0 (17.4) | 0.05 | 57.8 (16.7) | 59.8 (17.9) | 0.14 |
LRTI-VAS total score, mean (SD) | 21.0 (7.3) | 18.0 (7.5) | 0.02 | 21.0 (8.5) | 20.0 (7.1) | 0.18 |
Leicester Cough total score, mean (SD) | 13.4 (2.9) | 14.5 (3.2) | 0.02 | 13.8 (4.2) | 15.1 (2.6) | 0.09 |