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Table 5 Regional Ftis and ventilation parameters at baseline and during O2 + iNO

From: Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an imaging biomarker

Parameter

Control

PAH

Baseline

O2 + iNO

Baseline

O2 + iNO

Ftis

0.35 (0.31, 0.43)

0.39 (0.33, 0.49)

0.34 (0.27, 0.37)

0.37 (0.33, 0.41)

Volume (ml)

2107 (1521, 2646)

1940 (1421, 2347)

2223 (1676, 3209)

2147 (1282, 2997)

Mean s\({\dot{\rm V}}\)(10−3 s−1)

2.69 (1.49, 4.13)

2.92 (2.21, 3.51)

4.68 (1.82, 9.72)

3.33 (2.00, 5.91)

\({\dot{\rm V}}_{\rm A}\) (ml/min)

5.56 (3.73, 8.53)

5.55 (4.26, 6.72)

9.36 (4.22, 16.30)

6.31 (3.85, 7.84)

\({\text{CV}}^{2}_{{\dot{\rm V}}{\rm A}}\)

0.19 (0.07, 0.33)

0.18 (0.12, 0.24)

0.32 (0.07, 0.54)

0.28 (0.09, 0.37)

  1. Continuous variables are represented as mean (min, max)
  2. PAH: primary pulmonary arterial hypertension; Ftis: tissue fraction; Volume: gas volume; VA: alveolar ventilation; s\({\dot{\rm V}}\): specific ventilation (\({\dot{\rm V}}_{\rm A}\)/alveolar volume); \({\text{CV}}^{2}_{{\dot{\rm V}}{\rm A}}\): squared coefficient of variation quantifying heterogeneity in alveolar ventilation
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Respiratory Research

ISSN: 1465-993X

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