Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an imaging biomarker

Table 2 Vertical gradient and heterogeneity in perfusion

Continuous variables are represented as mean (min, max)
PAH: primary pulmonary arterial hypertension; Q_vgrad: vertical gradient in regional perfusion (slope); CV²_Qtotal: squared coefficient of variation in perfusion quantifying total spatial heterogeneity of perfusion (noise corrected); CV²_Qvgrad: squared coefficient of variation in perfusion quantifying heterogeneity generated by the dorsal–ventral gradient in perfusion; CV²_Qr: squared coefficient of variation in perfusion quantifying heterogeneity of the residual perfusion
^*Significant difference between measures at baseline and during administration of O₂ + iNO within a group
^†Significant difference between PAH subjects and controls at baseline
^‡Significant difference between PAH subjects and controls while breathing O₂ + iNO

ISSN: 1465-993X