Table 2 Univariate and multivariable logistic regression analyses of factors predicting PD-L1 TPS ≥ 50%
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Age | 1.025 (1.015, 1.036) |  < 0.001 | 1.008 (0.997, 1.020) | 0.160 |
Sex (male VS. female) | 3.528 (2.852, 4.364) |  < 0.001 | 1.623 (1.181, 2.232) | 0.003 |
Smoking history | 3.303 (2.727, 4.002) |  < 0.001 | 1.362 (1.016, 1.826) | 0.039 |
Histology |  |  < 0.001 |  |  < 0.001 |
 Adenocarcinoma | Reference |  | Reference |  |
 SQCC | 5.361 (4.369, 6.580) |  < 0.001 | 2.760 (2.174, 3.506) |  < 0.001 |
 LCC | 2.666 (1.281, 5.547) | 0.009 | 1.375 (0.645, 2.930) | 0.410 |
 ASC | 6.665 (2.920, 15.211) |  < 0.001 | 4.476 (1.909, 10.498) | 0.001 |
 Others | 4.557 (1.614, 12.870) | 0.004 | 3.107 (1.061, 9.100) | 0.039 |
TNM stage |  |  < 0.001 |  |  < 0.001 |
 0/IA | Reference |  | Reference |  |
 IB | 4.026 (2.954, 5.487) |  < 0.001 | 2.914 (2.110, 4.026) |  < 0.001 |
 II | 5.442 (4.141, 7.151) |  < 0.001 | 2.971 (2.212, 3.991) |  < 0.001 |
 III | 5.028 (3.919, 6.451) |  < 0.001 | 3.660 (2.822, 4.746) |  < 0.001 |
 IV | 3.262 (1.511, 7.039) | 0.003 | 3.706 (1.691, 8.123) | 0.001 |
 x | 7.675 (5.111, 11.524) |  < 0.001 | 6.542 (4.300, 9.954) |  < 0.001 |