Table 2 Association of smoking status with demographical and clinical features of patients with adenocarcinoma
|  | Ever Smoker (n = 143) | Never smoker (n = 698 ) | P values | P adj | ||||
|---|---|---|---|---|---|---|---|---|
Age at diagnosis | 59.3 ± 9.4 | 54.2 ± 12.7 | 0.0000015 | < 0.001 | ||||
Sex | male | 135 (94.41%) | 216 (30.95%) | 1.18e-44 | < 0.001 | |||
female | 8 (5.59%) | 482 (69.05%) | ||||||
T | Tis | 3 (2.24%) | 63 (9.20%) | Â | Â | |||
T1a | T1* | 26 (19.40%) | 100 (74.63%) | 230 (33.58%) | 517 (75.47%) | 0.067 | Ns | |
T1b | 56 (41.79%) | 208 (30.36%) | ||||||
T1c | 18 (13.43%) | 79 (11.53%) | ||||||
T2a | T2-T4 | 20 (14.93%) | 31 (23.13%) | 66 (9.64%) | 105 (15.33%) | |||
T2b | 5 (3.73%) | 9 (1.31%) | ||||||
T3 | 5 (3.73%) | 27 (3.94%) | ||||||
T4 | 1 (0.75%) | 3 (0.44%) | ||||||
N | N0* | 115 (80.42%) | 645 (92.41%) | 0.000014 | < 0.001 | |||
N1-N3 | 28 (19.48%) | 53 (7.59%) | ||||||
M | M0* | 141 (98.60%) | 689 (98.71%) | 1 | Ns | |||
M1 | 2 (1.40%) | 9 (1.29%) | ||||||
TNM | 0 | 3 (2.21%) | 62 (8.96%) | Â | Â | |||
IA1 | Less severe * | 25 (18.38%) | 113 (83.09%) | 228 (32.95%) | 592 (85.55%) | 0.00037 | < 0.001 | |
IA2 | 45 (33.09%) | 196 (28.32%) | ||||||
IA3 | 16 (11.76%) | 74 (10.69%) | ||||||
IB | 15 (11.03%) | 58 (8.38%) | ||||||
IIA | 3 (2.21%) | 6 (0.87%) | ||||||
IIB | 9 (6.62%) | 30 (4.34%) | ||||||
IIIA | Severe | 17 (12.50%) | 20 (14.71%) | 28 (4.05%) | 38 (5.49%) | |||
IIIB | 1 (0.74%) | 3 (0.43%) | ||||||
IV | 2 (1.47%) | 7 (1.01%) | ||||||