Skip to main content

Table 1 Baseline and therapeutic characteristics of patients before and after propensity score matching

From: Prophylactic cranial irradiation (PCI) versus active surveillance in patients with limited-stage small cell lung cancer: a retrospective, multicentre study

Characteristics

Before matching (%)

After matching (%)

PCI (n = 440)

Active surveillance (n = 628)

p value

PCI (n = 324)

Active surveillance (n = 324)

p value

Age, median (IQR), y

57 (51–63)

59 (52–64)

0.029

58 (51–64)

59 (51–65)

0.268

 < 65

356 (80.9)

473 (75.3)

0.031

255 (78.7)

240 (74.1)

0.165

 ≥ 65

84 (19.1)

155 (24.7)

 

69 (21.3)

84 (25.9)

 

Gender

 Male

312 (70.9)

434 (69.1)

0.528

232 (71.6)

229 (70.7)

0.795

 Female

128 (29.1)

194 (30.9)

 

92 (28.4)

95 (29.3)

 

ECOG PS

 0

52 (11.8)

91 (14.5)

0.427

41 (12.7)

39 (12)

0.609

 1

371 (84.3)

511 (81.4)

 

272 (84)

269 (83)

 

 2

17 (3.9)

26 (4.1)

 

11 (3.4)

16 (4.9)

 

Smoking status

 Never

188 (42.7)

263 (41.9)

0.831

138 (42.6)

139 (42.9)

0.762

 Former

40 (9.1)

64 (10.2)

 

27 (8.3)

32 (9.9)

 

 Current

212 (48.2)

301 (47.9)

 

159 (49.1)

153 (47.2)

 

Disease stage

 I–II

88 (20)

102 (16.2)

0.114

62 (19.1)

54 (16.7)

0.412

 III

352 (80)

526 (83.8)

 

262 (80.9)

270 (83.3)

 

Surgery

 Yes

31 (7)

54 (8.6)

0.356

29 (9)

28 (8.6)

0.89

 No

409 (93)

574 (91.4)

 

295 (91)

296 (91.4)

 

Chemotherapy

 Etoposide + platinum

428 (97.3)

601 (95.7)

0.12

315 (97.2)

309 (95.4)

0.212

 Others

11 (2.5)

27 (4.3)

 

9 (2.8)

15 (4.6)

 

CRT sequence

 Sequential

243 (55.2)

452 (72)

< 0.001

209 (64.5)

192 (59.3)

0.169

 Concurrent

197 (44.8)

176 (28)

 

115 (35.5)

132 (40.7)

 

Response to CRT

 PR

296 (67.3)

464 (73.9)

0.019

233 (71.9)

225 (69.4)

0.49

 CR

144 (32.7)

164 (26.1)

 

91 (28.1)

99 (30.6)

 
  1. PCI prophylactic cranial irradiation, IQR interquartile range, y years, ECOG PS Eastern Cooperative Oncology Group performance status, CRT chemoradiotherapy, CR complete response, PR partial response