Fig. 1From: Human umbilical cord mesenchymal stem cells combined with pirfenidone upregulates the expression of RGS2 in the pulmonary fibrosis in miceTherapeutic effects of different doses of PFD in bleomycin (BLM)-induced pulmonary fibrosis in mice. A The Kaplan–Meier survival curves of different doses of PFD groups (n = 10 each group). B The total soluble collagen content in the right lungs of different groups of mice (μg/right lung) (n = 10). C, E Representative pictures of hematoxylin–eosin (HE) and Masson staining of lung sections of different groups of pulmonary fibrosis mice. Scale bars: 200 μm. D, F The Ashcroft score of HE and Masson staining of different groups of pulmonary fibrosis mice (n = 3–4). G, H, I The mRNA levels of main pulmonary fibrosis markers (Col1a1, Col1a2, and α-SMA) of different groups of mice. Values are means ± SEM (n = 3). *p < 0.05; **p < 0.01; ***p < 0.01Back to article page