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Table 4 Analysis of central and effector memory T cells in the main T-cell populations based on CD4/CD8 expression in the four study groups

From: Central and effector memory T cells in peripheral blood of patients with interstitial pneumonia: preliminary clues from a COVID-19 study

 

PCR−Pn+

PCR+Pn+

PCR+Pn−

Controls

p-value

CD4+ T cells

 CD45RO+CCR7+ (% CD4+T)

29.59 ± 12.56

31.40 ± 14.62

27.00 ± 8.25

23.25 ± 7.99

0.0077

 CD45RO+CCR7+ (109/L)

0.2563 ± 0.1799

0.2281 ± 0.1468

0.2427 ± 0.1481

0.1727 ± 0.0583

0.0014

 CD45RO+CCR7− (% CD4 + T)

27.94 ± 13.14

26.40 ± 11.68

28.57 ± 10.53

35.55 ± 11.96

0.0191

 CD45RO+CCR7− (109/L)

0.2388 ± 0.1661

0.1838 ± 0.1116

0.2385 ± 0.1087

0.2661 ± 0.0969

ns

CD8+T cells

 CD45RO+CCR7− (% CD4+T)

10.80 ± 8.20

10.57 ± 11.55

6.57 ± 4.50

5.11 ± 4.14

< 0.0001

 CD45RO+CCR7+ (109/L)

0.0484 ± 0.0575

0.0347 ± 0.0450

0.0307 ± 0.0248

0.0207 ± 0.0188

0.0406

 CD45RO+CCR7− (% CD8+T)

29.71 ± 13.22

32.02 ± 13.10

39.15 ± 12.36

42.33 ± 14.03

< 0.0001

 CD45RO+CCR7− (109/L)

0.1323 ± 0.0955

0.1122 ± 0,0826

0.2044 ± 0,1017

0.1718 ± 0.0933

0.0013

DNT cells

 CD45RO+CCR7+ (% DNT)

7.89 ± 10.77

8.75 ± 10.72

8.90 ± 5.29

2.54 ± 1.97

0.0327

 CD45RO+CCR7+ (109/L)

0.0037 ± 0.0110

0.0032 ± 0.0046

0.0059 ± 0.0038

0.0011 ± 0.0010

ns

 CD45RO+CCR7− (% DNT)

40.31 ± 19.18

35.14 ± 20.28

51.86 ± 22.02

54.66 ± 17.45

0.0001

 CD45RO+CCR7− (109/L)

0.189 ± 0.0205

0.174 ± 0.0249

0.0437 ± 0.0331

0.243 ± 0.0168

0.0148

DPT cells

 CD45RO+CCR7+ (% DPT)

22.17 ± 17.55

19.56 ± 10.07

11.84 ± 7.28

6.22 ± 4.65

< 0.0001

 CD45RO+CCR7+ (109/L)

0.0080 ± 0.0089

0.0030 ± 0.0052

0.0018 ± 0.0025

0.0008 ± 0.0011

< 0.0001

 CD45RO+CCR7− (% DPT)

50.31 ± 19.98

44.58 ± 21.22

61.31 ± 19.46

71.85 ± 16.61

< 0.0001

 CD45RO+CCR7− (109/L)

0.0027 ± 0.0042

0.0075 ± 0.0124

0.0069 ± 0.0040

0.0099 ± 0.0113

0.001

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Respiratory Research

ISSN: 1465-993X

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