Fig. 6
From: Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC
A Effects of inhaled mosliciguat under thromboxane A2-induced PH in minipigs with and without pretreatment by ODQ. B Effects of mosliciguat after inhaled application under thromboxane A2-induced PH in minipigs with and without pretreatment by L-NAME. Data are mean ± SEM (n = 3). BP mean blood pressure, L-NAME N(G)-Nitro-l-arginine methyl ester, ODQ 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, PAP mean pulmonary arterial pressure, SEM standard error of the mean, wo without