Fig. 5
From: Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC
A Efficacy of inhaled mosliciguat on PAP (mean) and BP (mean) compared with efficacy of systemic applied bosentan and sildenafil at steady-state concentrations. B Efficacy of inhaled mosliciguat on PAP (mean) and BP (mean) in combination with bosentan or sildenafil under constant infusions. Results show percentage changes versus vehicle-treated control animals as mean ± SEM out of three or four experiments. BP mean blood pressure, PAP mean pulmonary arterial pressure, SEM standard error of the mean