Fig. 3
From: Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC
A Percentage changes in PAP (mean) and BP (mean) versus vehicle-treated animals after inhaled cumulative application of mosliciguat under thromboxane A2-induced PH in minipigs observed 30 min after inhalation of cumulative doses. Data are mean ± SEM (n = 3). B Percentage changes on PAP (mean) and BP (mean) versus vehicle-treated animals after cumulative infusions of mosliciguat under thromboxane A2-induced PH in minipigs observed 30 min after infusion of cumulative doses. Data are mean ± SEM (n = 3). BP mean blood pressure, PH pulmonary hypertension, PAP mean pulmonary arterial pressure, SEM standard error of the mean