Fig. 10
From: Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC
Left: bronchodilating effects on lung resistance at baseline prior to acetylcholine provocation (mean ± SEM, *p < 0.05, **p < 0.01 versus positive control group). Right: bronchoprotective effects after acetylcholine-induced bronchospasm: maximum lung resistance during and after provocation. Values are given as individual data and mean ± SEM with n = 11–17 animals/group and **p < 0.01 versus positive control group. RL lung resistance, SEM standard error of the mean