From: Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility
 | SALIA study sample |
---|---|
N | 296 |
Airway inflammatory biomarkers | |
 Arithmetic mean tumor necrosis factor-α (TNF-α) [pg/ml] (sd) | 2.5 (2.4) [N = 292] |
 Geometric mean TNF-α [pg/ml] (gsd) | 1.8 (2.1) [N = 292] |
 Mean loge-TNF-α [pg/ml] (sd) | 0.6 (0.7) [N = 292] |
 Arithmetic mean leukotriene (LT) B4 [pg/ml] (sd) | 867.0 (797.5) |
 Geometric mean LTB4 [pg/ml] (gsd) | 646.3 (2.1) |
 Mean loge-LTB4 [pg/ml] (sd) | 6.5 (0.8) |
 Arithmetic mean total number of cells [× 105] (sd) | 23.0 (26.3) |
 Geometric mean total number of cells [× 105] (gsd) | 14.8 (2.7) |
 Mean loge-total number of cells [× 105] (sd) | 2.7 (1.0) |
 Arithmetic mean tumor necrosis factor-α (TNF-α) [pg/ml] (sd) | 867.0 (797.5) |
Study characteristics | |
 Mean age ± sd | 74.4 ± 2.7 |
 Mean body mass index [kg/m2] ± sd | 27.6 ± 4.6 |
 Less than 10 years education of the participant or spouse (%) | 51 (17.2) |
 10 years maximal education of the participant or spouse (%) | 150 (50.7) |
 More than 10 years of the participant or spouse (%) | 95 (32.1) |
 Ever smoker (%) | 49 (16.6) |
 Second-hand smoking (%) | 173 (58.5) |
 Indoor mould (%) | 45 (15.2) |
 Heating with fossil fuels (%) | 44 (15.2) [n = 289] |
 Chronic inflammatory respiratory conditions | 81 (27.7) |
Air pollution exposure | |
 Median chronic NO2 exposure [µg/m3] (IQR) | 29.8 (10.3) |
 Median chronic NOx exposure [µg/m3] (IQR) | 46.5 (27.5) |
 Median chronic PM2.5 exposure [µg/m3] (IQR) | 25.8 (2.8) |
 Median chronic PM10 exposure [µg/m3] (IQR) | 38.8 (3.0) |
 Median chronic PMcoarse exposure [µg/m3] (IQR) | 13.4 (2.7) |
 Median chronic PM2.5 absorbance exposure [10–5/m] (IQR) | 2.0 (0.6) |