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Table 2 Pulmonary function test of patients at follow-up

From: Lung function and radiological findings 1 year after COVID-19: a prospective follow-up

 

First follow-up (2 months)

n = 377

Second follow-up (6 months)

n = 312

Third follow-up (12 months)

n = 284

p-value

FVC, L

3.50 (1.08)

3.55 (1.02)

3.66 (1.05)

< 0.001

FVC, % pred

98.99 (17.86)

100.76 (16.49)

104.16 (16.10)

< 0.001

FVC < 80%, pred

54 (14.32%)

29 (9.29%)

19 (6.69%)

< 0.001

FEV1, L

2.79 (0.86)

2.81 (0.82)

2.89 (0.84)

< 0.001

FEV1, % pred

98.58 (16.93)

100.12 (16.07)

103.53 (15.63)

< 0.001

FEV1/FVC

79.58 (6.87)

79.03 (6.30)

78.75 (5.92)

0.004

DLCO, % pred

78.47 (19.14)

81.61 (16.37)

84.03 (16.37)

< 0.001

DLCO < 80%, pred

203 (53.80%)

146 (46.79%)

113 (39.78%)

< 0.001

DLCO/VA, % pred

92.55 (17.37)

95.20 (17.25)

95.66 (17.16)

0.001

DLCO/VA < 80%, pred

83 (22.02%)

57 (18.26%)

48 (16.90%)

0.02

TLC, % pred

95.61 (14.90)

96.47 (14.33)

96.88 (14.51)

0.08

RV, % pred

96.90 (23.65)

96.75 (23.18)

95.02 (23.80)

0.72

6MWT distance, m

523.63 (94.30)

520.57 (104.53)

518.82 (101.66)

0.004

mMRCa

 0–1

216 (78.54%)

244 (88.72%)

248 (90.18%)

< 0.001

 ≥ 2

59 (21.45%)

31 (11.27%)

27 (9.82%)

 
  1. Data are n (%) or mean (SD)
  2. FVC forced vital capacity, FEV1 forced expiratory volume in one second, DLCO diffusing capacity for carbon monoxide, VA alveolar volume, TLC total lung capacity, RV residual volume, 6MWT 6 min walk test (m), mMRC modified British Medical Research Council (dyspnea)
  3. aDyspnea was registered on 275 patients