Skip to main content

Table 6 Health-related resources used for AE-IPF events along the study according to predicted FVC% at baseline

From: Clinical management and acute exacerbations in patients with idiopathic pulmonary fibrosis in Spain: results from the OASIS study

 

Total

N = 28

FVC < 50%

N = 9

FVC 50–80%

N = 16

FVC > 80%

N = 3

p-value

Visits

Primary care visits due to AE-IPF, n (%)

8 (28.6%)

4 (44.4%)

2 (12.5%)

2 (66.7%)

0.0760

Specialized care visits due to AE-IPF, n (%)

13 (46.4%)

4 (44.4%)

8 (50.0%)

1 (33.3%)

1.0000

Emergency visits related to AE-IPF, n (%)

21 (75.0%)

6 (66.7%)

14 (87.5%)

1 (33.3%)

0.1019

 Primary care areaa

6 (28.6%)

4 (66.7%)

1 (7.1%)

1 (100.0%)

0.0055

 Hospital care areaa

20 (95.2%)

6 (100.0%)

13 (92.9%)

1 (100.0%)

1.0000

Hospitalizations

Hospital admissions due to AE-IPF, n (%)

21 (75.0%)

8 (88.9%)

11 (68.8%)

2 (66.7%)

0.4529

Number of hospitalizations/event, mean (SD)

0.79 (0.50)

0.89 (0.33)

0.69 (0.48)

1.00 (1.00)

0.5133

Days of hospitalization, mean (SD)

8.48 (5.90)

10.50 (5.48)

8.17 (6.31)

4.33 (4.04)

0.2856

ICU admission, n (%)b

2 (8.7%)

0 (0.0%)

2 (16.7%)

0 (0.0%)

0.6206

Days in ICU, mean (SD)

18.50 (9.19)

18.50 (9.19)

Need for intubation, n (%)

2 (100.0%)

0 (0.0%)

2 (100.0%)

0 (0.0%)

Tests

Laboratory tests, n (%)c

16 (57.1%)

6 (66.7%)

8 (50.0%)

2 (66.7%)

0.8579

Pulmonary function tests, n (%)d

2 (7.1%)

0 (0.0%)

2 (12.5%)

0 (0.0%)

0.6190

Other tests, n (%)e

16 (57.1%)

6 (66.7%)

8 (50.0%)

2 (66.7%)

0.8579

Treatments

Pharmacological treatments for AE-IPF administered, n (%)

14 (50.0%)

5 (55.6%)

7 (43.8%)

2 (66.7%)

0.7575

Non-pharmacological treatments for AE-IPF administered, n (%)

6 (21.4%)

1 (11.1%)

5 (31.3%)

0 (0.0%)

0.4103

  1. In bold, p-values < 0.05
  2. AE-IPF acute exacerbation of IPF, FVC forced vital capacity, ICU intensive care unit, IPF idiopathic pulmonary fibrosis, SD standard deviation
  3. aOver 21 emergency visits
  4. bOver 23 admissions
  5. cIncluded: hemogram, biochemistry, coagulation profile, erythrocyte sedimentation rate, liver profile, C-reactive protein, procalcitonin, natriuretic peptide, dimer D and urine culture
  6. dIncluded: spirometry, carbon monoxide diffusion capacity, and 6-min walk test
  7. eIncluded: X-Ray, High resolution computed tomography (HRCT), arterial blood gases, respiratory virus screening, echocardiogram, and blood culture