Table 4 Changes in patient-reported outcomes from baseline to 2 weeks, 6 months, and 1 year after surgery

Overall

 mMRC dyspnea scale

  Adjusted mean (SE)

0.25 (0.03)

1.05 (0.03)

0.53 (0.03)

0.42 (0.03)

  Change from baseline (95% CI)^a

Reference

0.81 (0.74, 0.88)

0.28 (0.21, 0.36)

0.17 (0.10, 0.24)

 CAT total score

  Adjusted mean (SE)

5.97 (0.23)

12.77 (0.24)

7.29 (0.25)

6.22 (0.25)

  Change from baseline (95% CI)^a

Reference

6.79 (6.3, 7.29)

1.32 (0.8, 1.84)

0.24 (− 0.29, 0.77)

Type of surgery

 mMRC dyspnea scale

 Adjusted mean (SE)

  Wedge resection/segmentectomy

0.27 (0.06)

0.82 (0.06)

0.36 (0.07)

0.34 (0.07)

  Lobectomy

0.24 (0.03)

1.09 (0.03)

0.55 (0.03)

0.42 (0.03)

  Bilobectomy/pneumonectomy

0.13 (0.14)

1.44 (0.15)

0.83 (0.16)

0.65 (0.17)

  P-values

0.67

 < 0.01

 < 0.01

0.22

 Change from baseline (95% CI)^a

  Wedge resection/segmentectomy

Reference

0.55 (0.39, 0.71)

0.10 (− 0.06, 0.26)

0.07 (− 0.09, 0.24)

  Lobectomy

Reference

0.85 (0.76, 0.93)

0.30 (0.22, 0.39)

0.17 (0.09, 0.26)

  Bilobectomy/pneumonectomy

Reference

1.31 (0.95, 1.67)

0.78 (0.41, 1.16)

0.52 (0.13, 0.91)

  P for interaction

 < 0.01

 < 0.01

0.11

 CAT total score

 Adjusted mean (SE)

  Wedge resection/segmentectomy

6.08 (0.54)

11.61 (0.55)

6.55 (0.55)

5.78 (0.54)

  Lobectomy

5.83 (0.27)

13.09 (0.28)

7.42 (0.28)

6.28 (0.27)

  Bilobectomy/pneumonectomy

8.48 (1.27)

12.55 (1.3)

8.75 (1.34)

6.96 (1.31)

  P-values

0.12

0.02

0.12

0.2

 Change from baseline^a

  Wedge resection/segmentectomy

Reference

5.54 (4.43, 6.64)

0.47 (− 0.67, 1.61)

− 0.30 (− 1.48, 0.89)

  Lobectomy

Reference

7.26 (6.69, 7.83)

1.59 (1.00, 2.18)

0.45 (− 0.15, 1.05)

  Bilobectomy/pneumonectomy

Reference

4.07 (1.53, 6.61)

0.27 (-2.46, 3.00)

− 1.52 (− 4.31, 1.27)

  P for interaction

 < 0.01

0.17

0.25