Table 1 Comparison of baseline characteristics of participants
Non-COPD (n = 2141) | Young COPD (n = 95) | p value | |||
|---|---|---|---|---|---|
Never-smoker | Ever-smoker | Never-smoker | Ever-smoker | ||
Subjects (N) | 1294 | 847 | 36 | 59 | |
Age, years | 44.47 ± 5 | 44.37 ± 5 | 45.06 ± 6 | 44.98 ± 4 | 0.255 |
Sex, male (%) | 163 (12.6) | 761 (89.9) | 7 (19.4) | 55 (93.2) | < 0.001 |
BMI (kg/m2) | 23.87 ± 3.98 | 24.65 ± 3.83 | 23.54 ± 4.58 | 23.74 ± 3.90 | < 0.001 |
Smoking, pack-year | 0 | 18.77 ± 15.65 | 0 | 22.52 ± 15.00 | < 0.001 |
Comorbid condition | |||||
DM | 121 (9.4) | 99 (11.7) | 5 (13.9) | 7 (11.9) | 0.302 |
HTN | 194 (15.0) | 162 (19.1) | 4 (11.1) | 12 (20.3) | 0.053 |
Ischemic heart disease | 16 (1.24) | 18 (2.13) | 1 (2.78) | 3 (5.1) | 0.076 |
Congestive heart failure | 9 (0.7) | 4 (0.5) | 0 | 1 (1.7) | 0.630) |
Gastroesophageal reflux disease | 473 (36.6) | 247 (29.2) | 14 (38.9) | 20 (33.9) | 0.005 |
History of PTB | 8 (0.6) | 8 (0.94) | 2 (5.6) | 1 (1.7) | 0.012 |
Depression | 76 (5.9) | 28 (3.3) | 2 (5.6) | 7 (11.9) | 0.005 |
Atopic dermatitis | 57 (4.4) | 27 (3.2) | 3 (8.3) | 3 (5.1) | 0.270 |
Any allergya | 521 (40.3) | 295 (34.8) | 15 (41.7) | 18 (30.5) | 0.045 |
Asthma | 214 (16.5) | 96 (11.3) | 11 (30.6) | 7 (11.9) | < 0.001 |
Index of quality of life, EQ-5D | 0.97 ± 0.09 | 0.97 ± 0 | 0.95 ± 0.09 | 0.96 ± 0.09 | 0.224 |
Lung function | |||||
FEV1, % predicted | 93.79 ± 14.25 | 92.37 ± 13.42 | 72.91 ± 15.05 | 75.00 ± 14.81 | < 0.001 |
FVC, % predicted | 94.51 ± 14.32 | 93.38 ± 14.19 | 93.40 ± 15.42 | 94.27 ± 16.69 | 0.139 |
FEV1/FVC, % | 0.83 ± 0.06 | 0.81 ± 0.07 | 0.65 ± 0.06 | 0.65 ± 0.05 | < 0.001 |