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Table 3 Adjusted ORs and 95% CIs for the Association between POSA and ArTH according to CC and APOC

From: Prevalence, characteristics, and respiratory arousal threshold of positional obstructive sleep apnea in China: a large scale study from Shanghai Sleep Health Study cohort

Predictors

n

OR (95% CI)

Model 1

Model 2

Model 3

CC

    

 CC-NPOSA

3633

Reference

Reference

Reference

 Si-POSA

762

7.302 (6.090–8.757)***

6.990 (5.791–8.437)***

3.542 (2.862–4.384)***

 Sp-POSA

1353

1.567 (1.357–1.809)***

1.546 (1.331–1.795)**

1.043 (0.882–1.233)

APOC

    

 APOC-NPOSA

3283

Reference

Reference

Reference

 APOC I

781

8.159 (6.791–9.802)***

7.828 (6.471–9.471)***

3.900 (3.141–4.842)***

 APOC II

1455

2.134 (1.853–2.457)***

2.098 (1.812–2.429)***

1.287 (1.091–1.518)**

 APOC III

239

0.104 (0.046–0.236)***

0.118 (0.052–0.268)***

0.143 (0.062–0.330)***

  1. Model 1 was adjusted for age, BMI, and sex. Model 2 was adjusted for variables included in Model 1 and NC, WC, HC, alcohol consumption, smoking. Model 3 was adjusted for variables included in Model 2 and TST, ESS, MAI, CT90. OR odds ratio, CI confidence interval, POSA positional obstructive sleep apnea; ArTH, respiratory arousal threshold; CC, Cartwright Classification; APOC Amsterdam Positional Obstructive Sleep Apnea Classification; CC-NPOSA non-positional obstructive sleep apnea according to Cartwright Classification, Si-POSA supine-isolated positional obstructive sleep apnea; Sp-POSA, supine-predominant positional obstructive sleep apnea; APOC-NPOSA, non-positional obstructive sleep apnea according to Amsterdam Positional Obstructive Sleep Apnea Classification, BMI body mass index; NC neck circumference, WC waist circumference; HC, hip circumference; TST, total sleep time, ESS Epworth Sleepiness Scale, MAI micro-arousal index, CT90 the cumulative time spent at oxygen saturation below 90% in total sleep time. ** indicated p-value < 0.05 and *** indicated p-value < 0.001 for the logistic regression. NPOSA group was the reference category in each subgroup analysis