Table 3 Diagnostic performance analysis of serum parameters and severity score for CAP patients
| Â | Prediction of mortality | Prediction of ICU admission | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cut-off value | AUC (95% CI) | AUC (95% CI) § | Sensitivity (%) | Specificity (%) | Youden index | Cut-off value | AUC (95% CI) | AUC (95% CI) § | Sensitivity (%) | Specificity (%) | Youden index | |
NMI (pg/ml) | 55.48 | 0.91 (0.86–0.96) | 0.91 (0.85–0.95) | 87.10 | 85.12 | 0.72 | 55.48 | 0.92 (0.88–0.97) | 0.92 (0.88–0.96) | 86.96 | 88.22 | 0.75 |
PCT (ng/ml) | 0.89 | 0.79** (0.70–0.88) | 0.80 (0.70–0.88) | 64.52 | 86.61 | 0.51 | 0.80 | 0.80** (0.72–0.88) | 0.80 (0.73–0.88) | 65.32 | 87.76 | 0.53 |
CRP (mg/l) | 125.1 | 0.78** (0.69–0.87) | 0.78 (0.68–0.86) | 61.29 | 75.12 | 0.36 | 123.5 | 0.76*** (0.69–0.84) | 0.76 (0.69–0.83) | 56.51 | 85.30 | 0.42 |
WBC (10^9/l) | 13.15 | 0.59*** (0.47–0.71) | 0.59 (0.47–0.70) | 35.48 | 84.81 | 0.20 | 14.85 | 0.58*** (0.48–0.69) | 0.58 (0.47–0.68) | 32.61 | 90.20 | 0.23 |
Neutrophils (10^9/l) | 5.55 | 0.65*** (0.54–0.75) | 0.65 (0.54–0.74) | 80.65 | 45.73 | 0.26 | 11.20 | 0.63*** (0.53–0.72) | 0.63 (0.52–0.72) | 36.96 | 87.05 | 0.24 |
NCP(%) | 77.15 | 0.78** (0.70–0.86) | 0.78 (0.70–0.85) | 90.32 | 58.84 | 0.49 | 81.45 | 0.73*** (0.65–0.82) | 0.73 (0.65–0.82) | 69.57 | 72.33 | 0.42 |
PSI | 3.5 | 0.85&& (0.77–0.94) | 0.85 (0.77–0.92) | 88.43 | 77.42 | 0.66 | 3.5 | 0.84&&& (0.77–0.90) | 0.84 (0.77–0.90) | 65.22 | 89.66 | 0.55 |
N-PSI | 3.5 | 0.91 (0.86–0.96) | 0.91 (0.86–0.95) | 86.78 | 83.87 | 0.71 | 2.5 | 0.90 (0.86–0.94) | 0.90 (0.86–0.93) | 91.30 | 74.71 | 0.66 |
CURB65 score | 1.5 | 0.86## (0.77–0.95) | 0.86 (0.76–0.93) | 83.87 | 87.60 | 0.71 | 1.5 | 0.84### (0.76–0.91) | 0.84 (0.76–0.90) | 73.91 | 89.37 | 0.63 |
N-CURB65 score | 2.5 | 0.93 (0.89–0.97) | 0.93 (0.89–0.96) | 83.87 | 92.84 | 0.77 | 1.5 | 0.92 (0.89–0.96) | 0.92 (0.89–0.95) | 80.43 | 86.49 | 0.67 |