Fig. 4
From: NHLRC2 expression is increased in idiopathic pulmonary fibrosis
The number of fibroblast foci (FF) in idiopathic pulmonary fibrosis (IPF). The total number of FF were calculated from tissue sections of IPF patients (n = 47) with UIP histology in relation to the tissue section area. A Current smokers (n = 8) had less FF/cm2 compared to non-smokers (n = 17) (p < 0.001). There was a trend of ex-smokers (n = 18) having less FF/cm2 compared to non-smokers (n = 17) (p = 0.068) and current smokers having less FF/cm2 compared to ex-smokers (p = 0.078). B IPF patients with low percent predicted forced vital capacity (FVC%) (n = 20) had more FF/cm2 compared to patients who had high FVC% (n = 21) (p = 0.020)