Soluble RAGE in COPD, with or without coexisting obstructive sleep apnoea

Respiratory Research

Table 3 Univariate and multivariate association of sRAGE (log₁₀) with clinical characteristics in the whole cohort

Univariate	Beta	SE	t test	p Value
Age, years	− 0.0077	0.0182	2.91	< 0.001
BMI, kg/m²	− 0.0206	0.0045	4.55	< 0.001
Smoking, pack-years	− 0.0032	0.0007	4.15	< 0.001
FEV₁, % pred	0.0052	0.0009	6.01	< 0.001
AHI, events/h	− 0.0032	0.0008	4.06	< 0.001
T90, %	− 0.0078	0.0012	6.15	< 0.001
Multivariate
Age, years	− 0.0047	0.0344	1.82	0.061
BMI, kg/m²	− 0.0129	0.0141	2.33	0.027
Smoking, pack-years	− 0.0054	0.0124	2.71	0.019
FEV₁, % pred	0.0022	0.0005	3.16	0.002
AHI, events/h	− 0.0015	0.0005	2.63	0.012
T90, %	− 0.0039	0.0015	2.61	0.010

BMI body mass index, FEV₁ forced expiratory volume in 1 s, AHI apnoea–hypopnoea index, T90% of time with arterial oxygen saturation < 90%, sRAGE soluble receptor for advanced glycation end-products

ISSN: 1465-993X