Table 1 Baseline clinical characteristics of participants
From: Soluble RAGE in COPD, with or without coexisting obstructive sleep apnoea
Healthy nonsmokers | Smoker | OSA | COPD | Overlap | |
|---|---|---|---|---|---|
Number | 57 | 84 | 79 | 62 | 35 |
Age, years | 43.8 ± 12.0 | 51.8 ± 10.2 | 47.3 ± 9.6 | 60.6 ± 5.7 | 61.7 ± 4.7 |
Male, no. (%) | 30 (53) | 44 (52) | 64 (81) | 47 (68) | 29 (83) |
BMI, kg/m2 | 27.1 ± 4.3 | 26.1 ± 3.8 | 29.5 ± 3.5 | 26.3 ± 4.4 | 31.7 ± 5.1 |
Active smokers,% | 0 | 34 | 18 | 31 | 27 |
Smoking, pack-years | 0 | 21.3 ± 15.6 | 14.1 ± 17.4 | 41.2 ± 28.3 | 43.2 ± 24.7 |
FEV1, % pred | 98.2 ± 11.8 | 91.4 ± 14.5 | 96.1 ± 13.6 | 63.5 ± 20.1 | 60.2 ± 19.8 |
AHI, events/h | 2.4 ± 1.5 | 2.9 ± 1.4 | 43.7 ± 22.4 | 1.9 ± 2.1 | 29.6 ± 9.3 |
T90, % | 1.7 ± 4.9 | 2.7 ± 6.6 | 19.1 ± 19.9 | 11.4 ± 17.6 | 29.8 ± 23.6 |
ICS, no. (%) | 0 | 0 | 0 | 20 (32%) | 12 (34%) |
sRAGE, pg/mL | 1421 (1019–1740) | 1401 (1136–1731) | 1148 (773–1394) | 1066 (537–1281) | 1047 (757–1191) |