Fig. 5

Lipid ontology enrichment analysis (LION) was performed to associate lipids by infection type to chemical and biological features. Using the ranking mode, input lipids are ranked by numeric values and compared between two groups which included; A H1 vs H3; B H1 vs Rhino; C Rhino vs H3. D Enrichment analysis was also performed using the target-list mode where the subset of 35 lipids (N = 30) identified as driving the clustering was compared to the total set of lipids Significant enrichments based on p < 0.05 are shown for each analysis with the gray vertical lines indicating the cut-off value of significant enrichments based on q < 0.05. Bar colors are scaled with the enrichment (− log q-values)