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Table 3 The comparison of metabolites between PW children with and without prematurity during the follow-up

From: Metabolomics of bronchoalveolar lavage in children with persistent wheezing

 

PW children (median, 25%, 75%)

PW with recurrence (median, 25%, 75%)

Metabolites

Term infants (n = 21)#

Preterm infants (n = 9)#

P value

Term infants (n = 12)

Preterm infants (n = 5)

P value

Choline

132.77 (80.11, 176.97)

122.17 (84.08, 145.63)

0.874

135.90 (84.84, 172.05)

84.15 (68.01, 126.01)

0.292

Oleamide

0.30 (0.11, 1.10)

0.30 (0.14, 2.44)

0.769

0.23 (0.13, 1.64)

0.21 (0.05, 1.73)

0.598

Nepetalactam

0.08 (0.02, 0.92)

0.06 (0.00, 1.02)

0.946

0.31 (0.04, 1.02)

0.20 (0.002, 2.26)

0.833

Butyrylcarnitine

0.54 (0.25, 1.04)

1.20 (0.61, 1.91)

0.025*

0.47 (0.19, 0.78)

1.20 (0.68, 2.80)

0.027*

l-Palmitoylcarnitine

0.02 (0.01, 0.087)

0.02 (0.01, 0.08)

0.874

0.01 (0.005, 0.09)

0.02 (0.005, 0.11)

0.833

PC(16:0/16:0)

36.69 (16.44, 52.23)

33.73 (6.05, 56.49)

0.769

45.68 (13.06, 52.75)

7.21 (4.31, 31.01)

0.092

Palmitoylethanolamide

0.18 (0.07, 0.75)

0.31 (0.11, 1.94)

0.512

0.16 (0.05, 1.34)

0.15 (0.04, 1.48)

0.916

PC(22:2(13Z, 16Z)/14:0)

2.05 (0.90, 10.11)

1.48 (0.86, 7.51)

0.874

1.90 (0.67, 13.63)

0.92 (0.60, 9.18)

0.461

PC(16:0/14:0)

2.84 (0.58, 5.18)

1.44 (0.50, 29.06)

0.946

3.49 (0.94, 42.45)

1.44 (0.99, 20.16)

0.752

PC(22:4(7Z, 10Z, 13Z, 16Z)/14:0)

0.86 (0.62, 2.94)

0.69 (0.45, 4.14)

0.635

0.80 (0.51, 6.27)

0.48 (0.28, 2.81)

0.171

PC(18:1(11Z)/15:0)

0.17 (0.11, 0.42)

0.243 (0.12, 0.71)

0.455

0.19 (0.07, 0.38)

0.13 (0.08, 0.54)

0.673

PC(18:3(6Z,9Z,12Z)/18:0)

1.20 (0.79, 5.02)

0.91 (0.72, 3.39)

0.667

1.38 (0.54, 9.41)

0.83 (0.46, 6.06)

0461

PC(20:2(11Z, 14Z)/14:0)

9.10 (3.79, 28.02)

4.67 (2.63, 35.09)

0.635

11.34 (2.10, 72.33)

2.98 (1.68, 29.94)

0.246

  1. #Term infants refer to be born at a gestational age of 37–42 completed weeks, and preterm infants were defined as any birth before 37 weeks completed weeks of gestation. PC = phosphatidylcholines; PW = persistent wheezing. *P < 0.05